Article
Linkage disequilibrium maps constructed with common SNPs are useful for first-pass disease association screens.
Genomics - 1 Dec 2004
Taillon-Miller P, Saccone S F, Saccone N L, Duan S, Kloss E F, Lovins E G, Donaldson R, Phong A, Ha C, Flagstad L, Miller S, Drendel A, Lind D, Miller R D, Rice J P, Kwok P-Y
Abstract excerpt
To develop an efficient strategy for mapping genetic factors associated with common diseases, we constructed linkage disequilibrium (LD) maps of human chromosomes 5, 7, 17, and X. These maps consist of common single nucleotide polymorphisms at an average intermarker distance of 100 kb. The genoty...
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