Article
Intrinsic function of the aryl hydrocarbon (dioxin) receptor as a key factor in female reproduction.
Molecular and cellular biology - 1 Nov 2005
Baba Takashi, Mimura Junsei, Nakamura Naohito, Harada Nobuhiro, Yamamoto Masayuki, Morohashi Ken-Ichirou, Fujii-Kuriyama Yoshiaki
Abstract excerpt
Dioxins exert a variety of adverse effects on organisms, including teratogenesis, immunosuppression, tumor promotion, and estrogenic action. Studies using aryl hydrocarbon receptor (AhR)-deficient mice suggest that the majority of these toxic effects are mediated by the AhR. In spite of the adverse effects mediated by this receptor, the AhR gene is conserved among a number of animal species, ranging from...
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