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Article

Cigarette Smoke Exposure Leads to Follicle Loss via an Alternative Ovarian Cell Death Pathway in a Mouse Model

14 Oct 2011

Abstract excerpt

Cigarette smoking among reproductive-aged women is increasing worldwide. Cigarette smoking is a lifestyle behavior associated with important adverse health effects including subfertility and premature ovarian failure. We previously demonstrated that cigarette smoke (CS) exposure in mice decreases the primordial follicle pool; however, the mechanism of action is largely unknown. Therefore, the present study was...

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PMID: 22003194
DOI: 10.1093/toxsci/kfr279

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