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Article

Crosstalk between the protein surface and hydrophobic core in a core-swapped fibronectin type III domain.

Journal of molecular biology - 11 Jan 2008

Billings Kate S, Best Robert B, Rutherford Trevor J, Clarke Jane

Abstract excerpt

Two homologous fibronectin type III (fnIII) domains, FNfn10 (the 10th fnIII domain of human fibronectin) and TNfn3 (the third fnIII domain of human tenascin), have essentially the same backbone structure, although they share only approximately 24% sequence identity. While they share a similar folding mechanism with a common core of key residues in the folding transition state, they differ in many other physical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18035373
DOI: 10.1016/j.jmb.2007.10.056
PMCID: PMC2291452

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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