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Article

Designing an extracellular matrix protein with enhanced mechanical stability.

Proceedings of the National Academy of Sciences of the United States of America - 5 Jun 2007

Ng Sean P, Billings Kate S, Ohashi Tomoo, Allen Mark D, Best Robert B, Randles Lucy G, Erickson Harold P, Clarke Jane

Abstract excerpt

The extracellular matrix proteins tenascin and fibronectin experience significant mechanical forces in vivo. Both contain a number of tandem repeating homologous fibronectin type III (fnIII) domains, and atomic force microscopy experiments have demonstrated that the mechanical strength of these d...

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Identifiers

PMID: 17535921
DOI: 10.1073/pnas.0609901104
PMCID: PMC1887552

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17535921-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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