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Article

Mechanical design of the third FnIII domain of tenascin-C.

Journal of molecular biology - 13 Mar 2009

Peng Qing, Zhuang Shulin, Wang Meijia, Cao Yi, Khor Yuanai, Li Hongbin

Abstract excerpt

By combining single-molecule atomic force microscopy (AFM), proline mutagenesis and steered molecular dynamics (SMD) simulations, we investigated the mechanical unfolding dynamics and mechanical design of the third fibronectin type III domain of tenascin-C (TNfn3) in detail. We found that the mechanical stability of TNfn3 is similar to that of other constituting FnIII domains of tenascin-C, and the unfolding...

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Source

Identifiers

PMID: 19452631
DOI: 10.1016/j.jmb.2009.01.019

Genes

AFM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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