Article
Effective screening of informative single nucleotide polymorphisms using the novel method of restriction fragment mass polymorphism.
The Journal of international medical research - 1 Jan 2000
Hwang S-H, Oh H-B, Choi S-E, Hong S P, Yoo W
Abstract excerpt
Restriction fragment mass polymorphism (RFMP) was applied to pooled DNA for selecting informative single nucleotide polymorphisms (SNPs). A total of 225 coding non-synonymous SNPs (cnSNPs) from immunomodulating genes known to be involved in the pathogenesis of asthma were selected from the National Center for Biotechnology Information's (NCBI) SNP database (dbSNP). DNA samples from 200 healthy Koreans were...
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