Article
Machine learning approach to single nucleotide polymorphism-based asthma prediction.
PloS one - 1 Jan 2019
Gaudillo Joverlyn, Rodriguez Jae Joseph Russell, Nazareno Allen, Baltazar Lei Rigi, Vilela Julianne, Bulalacao Rommel, Domingo Mario, Albia Jason
Abstract excerpt
Machine learning (ML) is poised as a transformational approach uniquely positioned to discover the hidden biological interactions for better prediction and diagnosis of complex diseases. In this work, we integrated ML-based models for feature selection and classification to quantify the risk of individual susceptibility to asthma using single nucleotide polymorphism (SNP). Random forest (RF) and recursive feature...
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