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Article

Exploring rare and low-frequency variants in the Saguenay-Lac-Saint-Jean population identified genes associated with asthma and allergy traits.

European journal of human genetics : EJHG - 1 Jan 2019

Morin Andréanne, Madore Anne-Marie, Kwan Tony, Ban Maria, Partanen Jukka, Rönnblom Lars, Syvänen Ann-Christine, Sawcer Stephen, Stunnenberg Hendrik, Lathrop Mark, Pastinen Tomi, Laprise Catherine

Abstract excerpt

The Saguenay-Lac-Saint-Jean (SLSJ) region is located in northeastern Quebec and is known for its unique demographic history and founder effect. As founder populations are enriched with population-specific variants, we characterized the variants distribution in SLSJ and compared it with four European populations (Finnish, Sweden, United Kingdom and France), of which the Finnish population is another founder...

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Identifiers

PMID: 30206357
DOI: 10.1038/s41431-018-0266-4
PMCID: PMC6303288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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