Article
Single nucleotide polymorphisms in the promoter region of mir-133a-1 and in pre-mir-152 rs1707 may contribute to the risk of asthma in a Chinese Han population.
European review for medical and pharmacological sciences - 1 Jun 2016
Zhou P-P, Li Y, Ma Z-D, Li Z-Y, Chen F-Y, Jiang Y-X
Abstract excerpt
OBJECTIVE: microRNAs (miRNAs) play important roles in the pathogenesis of asthma. Single-nucleotide polymorphisms (SNPs) in the promotor regions of miRNAs or pre-miRNAs are involved in the alteration of miRNA expression levels or their maturation process and can contribute to asthma pathogenesis. PATIENTS AND METHODS: A total of 591 asthma cases and 621 controls were recruited for this study to evaluate the...
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