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Article

The helicase-like transcription factor and its implication in cancer progression.

Cellular and molecular life sciences : CMLS - 1 Feb 2008

Debauve G, Capouillez A, Belayew A, Saussez S

Abstract excerpt

The helicase-like transcription factor (HLTF) belongs to the SWI/SNF family of chromatin-remodeling factors. Several SWI/SNF genes are disrupted in cancer, suggesting their possible role as tumor suppressors. Similarly, the HLTF gene was found to be inactivated by hypermethylation in a significant number of colon, gastric and uterine tumors, indicating that HLTF silencing may confer a growth advantage and that...

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Source

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Identifiers

PMID: 18034322
DOI: 10.1007/s00018-007-7392-4
PMCID: PMC11131614

Genes

HLTF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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