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Article

HELQ in cancer and reproduction.

Neoplasma - 1 Jan 2016

Han X, Zhao L, Li X

Abstract excerpt

Helicase POLQ-like (HELQ), an ATP-dependent 3'-5' DNA helicase, plays pivotal roles in DNA processing, such as DNA replication, recombination and repair. The recent discovery of HELQ in mouse model and human cancer cell reveal that genetic alteration of HELQ is involved in cancer susceptibility and subfertility. Here we review the origin, function and mechanisms of HELQ in maintaining genomic stability....

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Source

Identifiers

PMID: 27565320
DOI: 10.4149/neo_2016_601

Genes

HELQ
POLQ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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