A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.

doi:10.1186/gb-2013-14-7-r82

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A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.

Genome biology - 31 Jul 2013

Simon Michelle M, Greenaway Simon, White Jacqueline K, Fuchs Helmut, Gailus-Durner Valérie, Wells Sara, Sorg Tania, Wong Kim, Bedu Elodie, Cartwright Elizabeth J, Dacquin Romain, Djebali Sophia, Estabel Jeanne, Graw Jochen, Ingham Neil J, Jackson Ian J, Lengeling Andreas, Mandillo Silvia, Marvel Jacqueline, Meziane Hamid, Preitner Frédéric, Puk Oliver, Roux Michel, Adams David J, Atkins Sarah, Ayadi Abdel, Becker Lore, Blake Andrew, Brooker Debra, Cater Heather, Champy Marie-France, Combe Roy, Danecek Petr, di Fenza Armida, Gates Hilary, Gerdin Anna-Karin, Golini Elisabetta, Hancock John M, Hans Wolfgang, Hölter Sabine M, Hough Tertius, Jurdic Pierre, Keane Thomas M, Morgan Hugh, Müller Werner, Neff Frauke, Nicholson George, Pasche Bastian, Roberson Laura-Anne, Rozman Jan, Sanderson Mark, Santos Luis, Selloum Mohammed, Shannon Carl, Southwell Anne, Tocchini-Valentini Glauco P, Vancollie Valerie E, Westerberg Henrik, Wurst Wolfgang, Zi Min, Yalcin Binnaz, Ramirez-Solis Ramiro, Steel Karen P, Mallon Ann-Marie, de Angelis Martin Hrabě, Herault Yann, Brown Steve D M

Abstract excerpt

BACKGROUND: The mouse inbred line C57BL/6J is widely used in mouse genetics and its genome has been incorporated into many genetic reference populations. More recently large initiatives such as the International Knockout Mouse Consortium (IKMC) are using the C57BL/6N mouse strain to generate null alleles for all mouse genes. Hence both strains are now widely used in mouse genetics studies. Here we perform a...

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PMID: 23902802
DOI: 10.1186/gb-2013-14-7-r82
PMCID: PMC4053787

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