Article
Complex haplotypes, copy number polymorphisms and coding variation in two recently divergent mouse strains.
Nature genetics - 1 May 2005
Adams David J, Dermitzakis Emmanouil T, Cox Tony, Smith James, Davies Rob, Banerjee Ruby, Bonfield James, Mullikin James C, Chung Yeun Jun, Rogers Jane, Bradley Allan
Abstract excerpt
Inbred mouse strains provide the foundation for mouse genetics. By selecting for phenotypic features of interest, inbreeding drives genomic evolution and eliminates individual variation, while fixing certain sets of alleles that are responsible for the trait characteristics of the strain. Mouse strains 129Sv (129S5) and C57BL/6J, two of the most widely used inbred lines, diverged from common ancestors within the...
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