Article
The contribution of the budding yeast histone H2A C-terminal tail to DNA-damage responses.
Biochemical Society transactions - 1 Dec 2007
Chambers A L, Downs J A
Abstract excerpt
The cellular response to DNA damage involves extensive interaction with and manipulation of chromatin. This includes the detection and repair of the DNA lesion, but there are also transcriptional responses to DNA damage, involving the up- or down-regulation of numerous genes. Therefore changes to chromatin structure, including covalent modification of histone proteins, are known to occur during DNA-damage...
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