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Article

Contribution of the serine 129 of histone H2A to chromatin structure.

Molecular and cellular biology - 1 May 2007

Fink Michel, Imholz Daniela, Thoma Fritz

Abstract excerpt

Phosphorylation of a yeast histone H2A at C-terminal serine 129 has a central role in double-strand break repair. Mimicking H2A phosphorylation by replacement of serine 129 with glutamic acid (hta1-S129E) suggested that phosphorylation destabilizes chromatin structures and thereby facilitates the access of repair proteins. Here we have tested chromatin structures in hta1-S129 mutants and in a C-terminal tail...

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Identifiers

PMID: 17353265
DOI: 10.1128/MCB.02077-06
PMCID: PMC1899979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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