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Article

Histone tails: Directing the chromatin response to DNA damage

26 May 2011

Abstract excerpt

Considerable energetic investment is devoted to altering large stretches of chromatin adjacent to DNA double strand breaks (DSBs). Immediately ensuing DSB formation, a myriad of histone modifications are elicited to create a platform for inducible and modular assembly of DNA repair protein complexes in the vicinity of the DNA lesion. This complex signaling network is critical to repair DNA damage and communicate...

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Identifiers

PMID: 21621538
DOI: 10.1016/j.febslet.2011.05.037

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