Article
Radiogenomics: the promise of personalized treatment in radiation oncology?
Clinical journal of oncology nursing - 1 Apr 2014
Proud Carol
Abstract excerpt
Significant variability exists in normal tissue reactions in patients with cancer receiving radiotherapy, with a subpopulation exhibiting increased toxicity to ionizing radiation. Genomic studies have proposed that single nucleotide polymorphisms in DNA repair genes, cytokines, and reactive oxygen species may play a role in clinical radiosensitivity. Additional research examining the association between genetic...
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