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Article

Radiogenomics: the promise of personalized treatment in radiation oncology?

Clinical journal of oncology nursing - 1 Apr 2014

Proud Carol

Abstract excerpt

Significant variability exists in normal tissue reactions in patients with cancer receiving radiotherapy, with a subpopulation exhibiting increased toxicity to ionizing radiation. Genomic studies have proposed that single nucleotide polymorphisms in DNA repair genes, cytokines, and reactive oxygen species may play a role in clinical radiosensitivity. Additional research examining the association between genetic...

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DNA Repair
Genomics
Mutation
Neoplasms
Polymorphism, Single Nucleotide
Precision Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24675253
DOI: 10.1188/14.CJON.185-189

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