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Article

Multiple primary melanomas in a CDKN2A mutation carrier exposed to ionizing radiation.

Archives of dermatology - 1 Nov 2007

Eliason Mark J, Hansen Chris B, Hart Marybeth, Porter-Gill Patricia, Chen Wei, Sturm Richard A, Bowen Glen, Florell Scott R, Harris Ronald M, Cannon-Albright Lisa A, Swinyer Leonard, Leachman Sancy A

Abstract excerpt

BACKGROUND: Recent research has shown a possible causal relationship between ionizing radiation exposure and melanoma. Individuals with mutations in CDKN2A (cyclin-dependent kinase inhibitor 2A), the major melanoma predisposition gene, have an increased susceptibility to melanoma-promoting exposures, such as UV light. We describe a patient from a familial melanoma pedigree with 7 primary melanomas on the right...

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Identifiers

PMID: 18025365
DOI: 10.1001/archderm.143.11.1409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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