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Article

Germline<i>CDKN2A</i>Mutation Status and Survival in Familial Melanoma Cases

10 Jun 2016

Abstract excerpt

BACKGROUND: Germline mutations in CDKN2A have been associated with increased risk of melanoma and tobacco-related cancers in respiratory and upper digestive tissues. In CDKN2A wild-type (wt) melanoma families, other known high-risk, melanoma-predisposing mutations are rare, and no increased risk has been observed for nonskin cancers in this group. This study is the first to compare survival in germline CDKN2A...

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PMID: 27287845
DOI: 10.1093/jnci/djw135

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