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Article

Clinical and histologic characteristics of malignant melanoma in families with a germline mutation in CDKN2A.

Journal of the American Academy of Dermatology - 1 Aug 2011

van der Rhee Jasper I, Krijnen Pieta, Gruis Nelleke A, de Snoo Femke A, Vasen Hans F A, Putter Hein, Kukutsch Nicole A, Bergman Wilma

Abstract excerpt

BACKGROUND: About 10% of cutaneous malignant melanomas (CMM) occur in individuals with a family history of melanoma. In 20% to 40% of melanoma families germline mutations in CDKN2A are detected. Knowledge of the clinicohistologic characteristics of melanomas and patients from these families is important for optimization of management strategies, and may shed more light on the complex interplay of genetic and...

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Identifiers

PMID: 21570156
DOI: 10.1016/j.jaad.2010.06.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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