Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Melanoma-prone families: new evidence of distinctive clinical and histological features of melanomas in CDKN2A mutation carriers.

Archives of dermatological research - 1 Dec 2018

Gironi Laura Cristina, Colombo Enrico, Pasini Barbara, Giorgione Roberto, Farinelli Pamela, Zottarelli Francesca, Esposto Elia, Zavattaro Elisa, Allara Elias, Ogliara Paola, Betti Marta, Dianzani Irma, Savoia Paola

Abstract excerpt

Germline mutations on the CDKN2A gene, the most important known genetic factors associated with cutaneous melanomas (CMs), predispose carriers to multiple primary CMs (MPMs) with higher frequency and younger onset compared to non-carriers. Most of the largest published studies concerning clinical and histological characteristics of CMs with CDKN2A mutation carriers did not specify if the described CMs are first...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Distribution
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Heredity

Share to Melanoma

Share to Sex Distribution

Share to Skin Neoplasms

Source

Identifiers

PMID: 30218143
DOI: 10.1007/s00403-018-1866-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Melanoma-prone families: new evidence of distinctive clinical and histological features of melanomas in CDKN2A mutation carriers.PMID 30218143Read ↗

Clinical and histopathological features of malignant melanoma in germline CDKN2A mutation families.Semantic proximity Read ↗

CDKN2a mutation-negative melanoma families have increased risk exclusively for skin cancers but not for other malignancies.Semantic proximity Read ↗

Clinical and histologic characteristics of malignant melanoma in families with a germline mutation in CDKN2A.Semantic proximity Read ↗

Germline Non-CDKN2A Variants in Melanoma and Associated Hereditary Cancer SyndromesSemantic proximity Read ↗

Temporal correlation between the first melanoma and the first noncutaneous tumor in CKDN2A genotyped patients.Semantic proximity Read ↗

Dermatologic surveillance in healthy carriers of CDKN2A and p.E318K MITF germline variants from melanoma-prone families: a 14 years hospital-based experience.Semantic proximity Read ↗

Familial Melanoma and Susceptibility Genes: A Review of the Most Common Clinical and Dermoscopic Phenotypic Aspect, Associated Malignancies and Practical Tips for ManagementSemantic proximity Read ↗

Hereditary melanoma: a five-year study of Brazilian patients in a cancer referral center - phenotypic characteristics of probands and pathological features of primary tumors.Semantic proximity Read ↗

Risks of Melanoma and Other Cancers in Melanoma-Prone Families over 4 Decades.Semantic proximity Read ↗

CDKN2A mutations could influence the dermoscopic pattern of presentation of multiple primary melanoma: a clinical dermoscopic genetic study.Semantic proximity Read ↗

Characterization of patients at high risk of melanoma in Austria.Semantic proximity Read ↗

Clinical, pathological and dermoscopic phenotype of MITF p.E318K carrier cutaneous melanoma patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.