Article
Drug induced superinfection in HIV and the evolution of drug resistance.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2008
Leontiev Vladimir V, Maury Wendy J, Hadany Lilach
Abstract excerpt
The rapid evolution of HIV drug resistance is a major cause of AIDS treatment failure. Superinfection, the infection of an already infected cell by additional virions, can be a major factor contributing to the evolution of drug resistance. However, the pattern and consequences of superinfection in HIV populations are far from fully understood. In this paper we study the implications of the fact that...
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