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Article

Genetic polymorphism in the manganese superoxide dismutase gene is associated with an increased risk for hepatocellular carcinoma in HCV-infected Moroccan patients.

Mutation research - 8 Jan 2008

Ezzikouri Sayeh, El Feydi Abdellah Essaid, Chafik Abdelaziz, Afifi Rajae, El Kihal Latifa, Benazzouz Mustapha, Hassar Mohammed, Pineau Pascal, Benjelloun Soumaya

Abstract excerpt

Hepatocellular carcinoma (HCC) ranks among the 10 most common cancers worldwide. The main risk factors for its development are hepatitis B and C virus infections. Hepatitis B and C viruses induce chronic inflammation and oxidative stress that could predispose a cell to mutagenesis and proliferation. Manganese superoxide dismutase (MnSOD) catalyses the detoxification of free radicals, thus playing a crucial role...

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Identifiers

PMID: 18023606
DOI: 10.1016/j.mrgentox.2007.05.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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