Article

White Matter Integrity Involvement in Preclinical Stage of Familial Creutzfeldt-Jakob Disease: A Diffusion Tensor Imaging Study

2020-07-15

Abstract excerpt

<h4>Background: </h4> : To explore the patterns of white matter (WM) alterations using diffusion tensor imaging (DTI) in the preclinical stage of familial Creutzfeldt-Jakob disease (fCJD) . <h4>Methods: </h4> 7 asymptomatic carriers of PRNP G114V mutation and 6 non-carriers from the same fCJD kindred were recruited at baseline. Follow-up was obtained in 7 asymptomatic carriers and 2 non-carriers 2 years later. We...

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Literature Corpus work: 0205445e-6b08-56ab-af7e-f046deb4f91d
DOI: 10.21203/rs.3.rs-41558/v1

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