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MRI reveals therapeutical efficacy of stem cells: An experimental study on the SOD1(G93A) animal model.

Magnetic resonance in medicine - 1 Jan 2018

Bontempi Pietro, Busato Alice, Bonafede Roberta, Schiaffino Lorenzo, Scambi Ilaria, Sbarbati Andrea, Mariotti Raffaella, Marzola Pasquina

Abstract excerpt

PURPOSE: The first part of the experiment identifies and validates MRI biomarkers distinctive of the disease progression in the transgenic superoxide dismutase gene (SOD1(G93A)) animal model. The second part assesses the efficacy of a mesenchymal stem cell-based therapy through the MRI biomarkers previously defined. METHODS: The first part identifies MRI differences between SOD1(G93A) and healthy mice. The second...

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PMID: 28370153
DOI: 10.1002/mrm.26685

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SOD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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