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Article

Cylindromatosis and the <i>CYLD</i> gene: new lessons on the molecular principles of epithelial growth control

15 Nov 2007

Abstract excerpt

Analysing cylindromatosis and the associated defects in the CYLD gene is providing novel insights into the molecular principles of epithelial growth control and carcinogenesis in, and beyond, the skin. In this review, we summarize the histopathology and histogenesis of cylindromas, and the available genetic information on patients with these skin appendage tumors. Focusing on recent data concerning the normal...

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PMID: 18008375
DOI: 10.1002/bies.20677

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Related research

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Research trail→

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Cylindromatosis and the <i>CYLD</i> gene: new lessons on the molecular principles of epithelial growth controlPMID 18008375Read ↗

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CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways.Semantic proximity Read ↗

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