Article
HIV-1 genotypic drug resistance interpretation rules - 2009 Spanish guidelines.
AIDS reviews - 1 Jan 2000
de Mendoza Carmen, Anta Lourdes, García Federico, Pérez-Elías M Jesús, Gutiérrez Félix, Llibre Josep M, Menéndez-Arias Luis, Dalmau David, Soriano Vincent
Abstract excerpt
Interpreting the results of drug resistance tests for HIV-1 is one of the most difficult tasks for both clinicians and virologists. There are many amino acid changes in viral proteins influencing the susceptibility to specific drugs, causing loss of activity or conversely hypersusceptibility. Moreover, the results of interactions derived from complex mutational patterns are difficult to predict. Different...
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