Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GATA-3 is expressed in association with estrogen receptor in breast cancer

20 Apr 1999

Abstract excerpt

To better understand the molecular basis for the hormone-responsive phenotype in breast cancer, we have used a human cDNA array to compare patterns of gene expression between breast carcinoma cell lines discordant for estrogen receptor (ER) expression. These experiments indicated abundant expression of the transcription factor GATA-3 in the ER-positive cell lines MCF7 and T-47D, with minimal or no expression in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Metastasis and carcinoma case studies
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10096242
DOI: 10.1002/(sici)1097-0215(19990420)84:2<122::aid-ijc5>3.0.co;2-s

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GATA-3 is expressed in association with estrogen receptor in breast cancerPMID 10096242Read ↗

Positive Cross-Regulatory Loop Ties GATA-3 to Estrogen Receptor α Expression in Breast CancerSemantic proximity Read ↗

GATA3 and markers of epithelial-mesenchymal transition predict long-term benefit from tamoxifen in ER-positive breast cancerSemantic proximity Read ↗

GATA3 mutation disrupts a functional network governed by estrogen receptor, FOXA1 and GATA3Semantic proximity Read ↗

Cancer-specific mutation of GATA3 disrupts the transcriptional regulatory network governed by Estrogen Receptor alpha, FOXA1 and GATA3.Semantic proximity Read ↗

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver.Semantic proximity Read ↗

The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer.Semantic proximity Read ↗

The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review.Semantic proximity Read ↗

Expression patterns of GATA3 and the androgen receptor are strongly correlated in patients with triple-negative breast cancerSemantic proximity Read ↗

The estrogen receptor/GATA3/FOXA1 transcriptional network: lessons learned from breast cancerSemantic proximity Read ↗

Mutation of GATA3 in human breast tumors.Semantic proximity Read ↗

Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover.Semantic proximity Read ↗

Common genetic variation in GATA-binding protein 3 and differential susceptibility to breast cancer by estrogen receptor alpha tumor status.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.