Article
SNPPicker: high quality tag SNP selection across multiple populations.
BMC bioinformatics - 2 May 2011
Sicotte Hugues, Rider David N, Poland Gregory A, Dhiman Neelam, Kocher Jean-Pierre A
Abstract excerpt
BACKGROUND: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every single SNP. However, existing tag SNP selection algorithms for designing custom genotyping panels do not take into account all platform dependent factors affecting the likelihood of a tag SNP to be successfully genotyped and many of the...
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