Article
Quantitative characterization of protein nanostructures using atomic force microscopy.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference - 1 Jan 2007
Segers-Nolten Ine, van der Werf Kees, van Raaij Martijn, Subramaniam Vinod
Abstract excerpt
The aggregation of proteins into fibrillar structures called amyloid is a characteristic of many diseases, including several neurodegenerative disorders. Although amyloid formation is inherent to several serious diseases, the mechanism of fibril formation and the modes of toxicity are not yet known. High concentrations of fibrillar aggregates of ¿-synuclein protein are found in the brains of patients suffering...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
