Article
Amyloid structure and assembly: insights from scanning transmission electron microscopy.
Journal of structural biology - 1 Jan 2011
Goldsbury Claire, Baxa Ulrich, Simon Martha N, Steven Alasdair C, Engel Andreas, Wall Joseph S, Aebi Ueli, Müller Shirley A
Abstract excerpt
Amyloid fibrils are filamentous protein aggregates implicated in several common diseases such as Alzheimer's disease and type II diabetes. Similar structures are also the molecular principle of the infectious spongiform encephalopathies such as Creutzfeldt-Jakob disease in humans, scrapie in shee...
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