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Article

The Mga virulence regulon: infection where the grass is greener

12 Nov 2007

Abstract excerpt

Co-ordinate regulation of virulence gene expression in response to different host environments is central to the success of the group A streptococcus (GAS, Streptococcus pyogenes) as an important human pathogen. Mga represents a ubiquitous stand-alone virulence regulator that controls genes (Mga regulon) whose products are necessary for adherence, internalization and host immune evasion. Mga highly activates a...

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PMID: 18001346
DOI: 10.1111/j.1365-2958.2007.06006.x

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