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The Catabolite Control Protein CcpA Binds to P mga and Influences Expression of the Virulence Regulator Mga in the Group A Streptococcus

29 Sept 2007

Abstract excerpt

Carbon catabolite repression (CCR) allows bacteria to alter metabolism in response to the availability of specific sugar sources, and increasing evidence suggests that CCR is involved in regulating virulence gene expression in many pathogens. A scan of the M1 SF370 group A streptococcus (GAS) genome using a Bacillus subtilis consensus identified a number of potential catabolite-responsive elements (cre) important...

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PMID: 17905980
DOI: 10.1128/jb.01038-07

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