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Novel motif associated with carbon catabolite repression in two major Gram-positive pathogen virulence regulatory proteins

10 Oct 2024

Abstract excerpt

ABSTRACT Carbon catabolite repression (CCR) is a widely conserved regulatory process that ensures enzymes and transporters of less-preferred carbohydrates are transcriptionally repressed in the presence of a preferred carbohydrate. This phenomenon can be regulated via a CcpA-dependent or CcpA-independent mechanism. The CcpA-independent mechanism typically requires a transcriptional regulator harboring a...

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PMID: 39387597
DOI: 10.1128/spectrum.00485-24

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