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Article

[Relationship between CpG island methylator phenotype and genetic instability in sporadic colorectal cancer].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 1 Nov 2007

Cai Guo-Xiang, Xu Ye, Cai San-Jun, Shi Ying-Qiang, Lian Peng, Peng Jun-Jie, Guan Zu-Qing, Du Xiang

Abstract excerpt

OBJECTIVE: To explore the relationship between CpG island methylator phenotype(CIMP) and genetic instability in sporadic colorectal cancer(SCRC). METHODS: Seventy-one SCRC patients were enrolled in this study. Promotor methylation status of five genes including P14(ARF ), hMLH1, P16(INK4a), MGMT and MINT1 was detected with methylation specific PCR to confirm CIMP. Microsatellite instability (MSI) status was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 18000779

Genes

MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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