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Article

Blood coagulation at the site of microvascular injury in healthy and coumadin-treated subjects heterogenous for factor V Leiden mutation.

Thrombosis and haemostasis - 1 Nov 2007

Undas Anetta, Brzezinska-Kolarz Beata, Orfeo Tom, Brummel-Ziedins Kathleen, Musial Jacek, Szczeklik Andrew, Mann Kenneth G

Abstract excerpt

There is little knowledge regarding the in-vivo course of coagulation reactions in subjects with factor (F)V Leiden (G1691A, R506Q). The aim of the current study was to evaluate the effect of FV Leiden on coagulant reactions triggered by vascular injury. At the site of microvascular injury, prothrombin activation and FVa formation and inactivation have been evaluated in 16 apparently healthy subjects and 16...

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PMID: 18000607
DOI: 10.1160/th07-04-0302

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APC
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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