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Article

Patterns of mutation and selection at synonymous sites in Drosophila.

Molecular biology and evolution - 1 Dec 2007

Singh Nadia D, Bauer DuMont Vanessa L, Hubisz Melissa J, Nielsen Rasmus, Aquadro Charles F

Abstract excerpt

That natural selection affects molecular evolution at synonymous sites in protein-coding sequences is well established and is thought to predominantly reflect selection for translational efficiency/accuracy mediated through codon bias. However, a recently developed maximum likelihood framework, when applied to 18 coding sequences in 3 species of Drosophila, confirmed an earlier report that the Notch gene in...

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Identifiers

PMID: 18000010
DOI: 10.1093/molbev/msm196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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