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Article

Variable strength of translational selection among 12 Drosophila species.

Genetics - 1 Nov 2007

Heger Andreas, Ponting Chris P

Abstract excerpt

Codon usage bias in Drosophila melanogaster genes has been attributed to negative selection of those codons whose cellular tRNA abundance restricts rates of mRNA translation. Previous studies, which involved limited numbers of genes, can now be compared against analyses of the entire gene complements of 12 Drosophila species whose genome sequences have become available. Using large numbers (6138) of orthologs...

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Identifiers

PMID: 18039870
DOI: 10.1534/genetics.107.070466
PMCID: PMC2147958

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Source receipt: pubmed, retrieved 7 Sept 2026.

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