Article
Genetic polymorphisms and haplotype structures of the human CYP2W1 gene in a Japanese population.
Drug metabolism and disposition: the biological fate of chemicals - 1 Feb 2008
Hanzawa Yoshiyuki, Sasaki Takamitsu, Mizugaki Michinao, Ishikawa Masaaki, Hiratsuka Masahiro
Abstract excerpt
A novel human cytochrome P450, designated CYP2W1, has recently been identified and is found to be present mainly in tumor cells, particularly in colon cancer cells. In the present study, we report the first systematic investigation of polymorphisms in the human CYP2W1 gene. Based on denaturing high performance liquid chromatography analyses of polymerase chain reaction products, we analyzed nine exons and...
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