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Article

Expression of CYP2W1 in colon tumors: Regulation by Gene Methylation

1 Oct 2007

Abstract excerpt

INTRODUCTION: CYP2W1 is a novel enzyme shown to be selectively expressed in rat fetal colon and in human colon cancer and has previously been suggested as a potential drug target for cancer therapy. Here, the expression and gene methylation of CYP2W1 were analyzed in human colon carcinoma cell lines, colon tumors and in corresponding normal colon tissue. METHODS: CYP2W1 mRNA and protein expression in HepG2 and...

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PMID: 17979506
DOI: 10.2217/14622416.8.10.1315

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