Article
Genetic polymorphisms of CYP2C8 in Japanese population.
Drug metabolism and disposition: the biological fate of chemicals - 1 Jun 2003
Nakajima Miki, Fujiki Yuto, Noda Kumiko, Ohtsuka Hiroki, Ohkuni Hisashi, Kyo Satoru, Inoue Masaki, Kuroiwa Yukio, Yokoi Tsuyoshi
Abstract excerpt
CYP2C8 plays important roles in metabolizing therapeutic drugs and endogenous compounds. Although genetic polymorphisms of CYP2C8 were reported, there is little information on CYP2C8 polymorphisms in the Japanese population. In the present study, we screened for previously described polymorphisms in the coding region of this gene using polymerase chain reaction (PCR)-restriction fragment length polymorphism or...
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