Article
CYP2W1 variant alleles in Caucasians and association of the CYP2W1 G541A (Ala181Thr) polymorphism with increased colorectal cancer risk.
Pharmacogenomics - 1 Jul 2010
Gervasini Guillermo, de Murillo Silvia Gonzalez, Ladero Jose M, Agúndez Jose A G
Abstract excerpt
AIMS: To detect differences in the frequency of the known nonsynonymous CYP2W1 polymorphisms between colorectal cancer patients and healthy subjects. MATERIALS & METHODS: The study group consisted of 150 colorectal patients and 263 controls. The presence of five nonsynonymous CYP2W1 polymorphisms was analyzed by novel amplification-restriction methods. RESULTS: Two nonsynonymous SNPs causing the amino acid...
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