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Article

Polymorphisms of the interleukin-6 gene promoter and abdominal aortic aneurysm.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 Jan 2008

Smallwood L, Allcock R, van Bockxmeer F, Warrington N, Palmer L J, Iacopetta B, Norman P E

Abstract excerpt

BACKGROUND: Elevated levels of circulating interleukin-6 (IL-6) have been reported in patients with abdominal aortic aneurysms (AAAs). Although this implicates inflammation as a cause of AAAs, there is also evidence that the aneurysmal aorta may secrete IL-6 into the circulation as a result of aortic proteolysis. Genetic association studies are one means of trying to clarify the role of specific mediators in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17996468
DOI: 10.1016/j.ejvs.2007.08.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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