The interleukin-10-1082 'A' allele and abdominal aortic aneurysms.

doi:10.1016/j.jvs.2007.06.025

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The interleukin-10-1082 'A' allele and abdominal aortic aneurysms.

Journal of vascular surgery - 1 Oct 2007

Bown Matthew J, Lloyd Geraint M, Sandford Rebecca M, Thompson John R, London Nicholas J M, Samani Nilesh J, Sayers Robert D

Abstract excerpt

BACKGROUND: Abdominal aortic aneurysms (AAA) are caused by inflammatory processes in the wall of the aorta resulting in degradation of structural proteins. This inflammatory process is mediated, in part, by cytokines, and interleukin-10 (IL-10) is a predominantly anti-inflammatory cytokine. A single nucleotide polymorphism in the promoter region of the IL-10 gene that affects transcription has been associated...

Topics

Aged
Aged, 80 and over
Alleles
Aortic Aneurysm, Abdominal
Case-Control Studies
Female
Gene Frequency
Genotype
Humans
Interleukin-10
Male
Middle Aged
Polymorphism, Single Nucleotide
Promoter Regions, Genetic

Source

Open in PubMed

Identifiers

PMID: 17903648
DOI: 10.1016/j.jvs.2007.06.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics