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Article

Polymorphisms in the IL-6 and TNF-α gene are associated with an increased risk of abdominal aortic aneurysm.

International journal of cardiology - 15 Apr 2021

Jabłońska Agnieszka, Zagrapan Branislav, Neumayer Christoph, Eilenberg Wolf, Scheuba Andreas, Brostjan Christine, Demyanets Svitlana, Klinger Markus, Nanobachvili Josif, Huk Ihor

Abstract excerpt

BACKGROUND: An abdominal aortic aneurysm (AAA) is a complex disease of the aging population that is associated with inflammation and the cellular immune response. To investigate the influence of interleukin (IL)-6 and tumor necrosis factor (TNF)-α single nucleotide polymorphisms (SNPs) on the ris...

Topics

Aged
Aortic Aneurysm, Abdominal
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-6
Polymorphism, Single Nucleotide
Tumor Necrosis Factor-alpha

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33359288
DOI: 10.1016/j.ijcard.2020.12.051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-33359288-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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