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Article

N-cadherin is required for the polarized cell behaviors that drive neurulation in the zebrafish.

Development (Cambridge, England) - 1 Oct 2006

Hong Elim, Brewster Rachel

Abstract excerpt

Through the direct analysis of cell behaviors, we address the mechanisms underlying anterior neural tube morphogenesis in the zebrafish and the role of the cell adhesion molecule N-cadherin (N-cad) in this process. We demonstrate that although the mode of neurulation differs at the morphological level between amphibians and teleosts, the underlying cellular mechanisms are conserved. Contrary to previous reports,...

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Identifiers

PMID: 16943271
DOI: 10.1242/dev.02560

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