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Article

Cell autonomous commitment to an endodermal fate and behaviour by activation of Nodal signalling.

Development (Cambridge, England) - 1 Oct 2001

David N B, Rosa F M

Abstract excerpt

In vertebrates the endoderm germ layer gives rise to most tissues of the digestive tract and controls head and heart morphogenesis. The induction of endoderm development relies on extracellular signals related to Nodals and propagated intracellularly by TGFbeta type I receptors ALK4/Taram-A. It is unclear, however, whether Nodal/ALK4/Taram-A signalling is involved only in the specification of endodermal...

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Identifiers

PMID: 11641218
DOI: 10.1242/dev.128.20.3937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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