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Article

Direct development of functionally mature tryptase/chymase double-positive connective tissue-type mast cells from primate embryonic stem cells.

Stem cells (Dayton, Ohio) - 1 Mar 2008

Ma Feng, Kambe Naotomo, Wang Dan, Shinoda Gen, Fujino Hisanori, Umeda Katsutsugu, Fujisawa Akihiro, Ma Lina, Suemori Hirofumi, Nakatsuji Norio, Miyachi Yoshiki, Torii Ryuzo, Tsuji Kohichiro, Heike Toshio, Nakahata Tatsutoshi

Abstract excerpt

Conditions that influence the selective development or recruitment of connective tissue-type and mucosal-type mast cells (MCs) are not well understood. Here, we report that cynomolgus monkey embryonic stem (ES) cells cocultured with the murine aorta-gonad-mesonephros-derived stromal cell line AGM-S1 differentiated into cobblestone (CS)-like cells by day 10-15. When replated onto fresh AGM-S1 with the addition of...

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Identifiers

PMID: 17991916
DOI: 10.1634/stemcells.2007-0348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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