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Article

Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells.

Proceedings of the National Academy of Sciences of the United States of America - 4 Oct 2005

Hsieh F H, Sharma P, Gibbons A, Goggans T, Erzurum S C, Haque S J

Abstract excerpt

Mast cells (MCs) are found in increased numbers at airway mucosal surfaces in asthmatic patients. Because human airway epithelial cells (HAECs) actively participate in airway inflammatory responses and are in direct contact with MCs in the mucosa, we hypothesized that HAEC-MC interactions may contribute to the differentiation and survival of MCs in the airway mucosa. Here, we show that HAECs express mRNA and...

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Identifiers

PMID: 16186496
DOI: 10.1073/pnas.0503948102
PMCID: PMC1242292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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